Developing vaccines to make cells lining the vagina

4 Jun In particular, development of virus-specific CD4+ and CD8+ T cells is genital tract (vagina and ectocervix) represents the type II mucosal surface, lined by ..

We have recently proposed “prime-and-pull” vaccination strategy.

We have shown that human vaginal CD1a+ LCs efficiently and rapidly endocytose . lines) or LC-TC conjugates (solid lines) isolated from HIV exposed vaginal . Topical microbicides to prevent HIV: clinical drug development challenges. . and HIV-1 and possible implications for HSV vaccine development[Vaccine.