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Description:In addition to potential feelings of isolation and embarrassment, early puberty is linked to earlier sexual activity, which can lead to emotional damage as well as unwanted pregnancies and sexually transmitted diseases. It would then be for those in charge of health spending to decide whether the risks of later disease and the other problems associated with early breast development are grave enough to justify this course of action. At this stage, however, there are grounds for optimism. There is evidence of early puberty leading to increased risk of obesity, type 2 diabetes, heart disease and cancer — particularly breast cancer. Until now it had not been clear how these cells arrive at the correct place and time. We found that mice that do not have ACKR2 start puberty early because the macrophage cells arrive in the breasts prematurely.
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